The shape of DNA

Graphical abstract: Molecular biologists and biochemists are quite sensitive on the topic of DNA representation. Many of them will be triggered when the looping of the DNA is misrepresented as a left-handed helix instead of a right-handed one (what we mean by that is that when one looks at DNA from ‘within’ the helix, they turn clock-wise as they get more distant). I am not quite offended by this mistake, as I hardly remember if (B-)DNA is right-handed or left-handed, and what right-handed and left-handed means in the context of an helix.